PROGRAMME & AGENDA

iscbAI 2025 Agenda

May 31st

8:25

Gathering at Prama Sanur Beach Hotel

8:25-8:45

Shuttle Bus to Tsinghua Southeast Asia Center

8:45-9:00

Sign-in and get badge

9:00 -9:05

Opening Remarks - Xuegong Zhang

9:05-9:35

Keynotes

I-TASSER: Bridging Deep Learning and Physics-Based Simulation for Next-Generation Protein Folding

Speaker: Yang Zhang

Moderator: Xingming Zhao

 

 

 

9:35-10:35

Session 1 Interpretable AI models for biology and medicine

Moderator:Rui Jiang/Yong Wang/Zhen Xie

9:35-9:45  Tsung Fei KHANG

When Deep Learning Meets Traditional Taxonomy: Divergent Feature Interpretation in Fly Wing Venation Analysis

9:45-9:55  Hong Li

Interpretable AI Model to Identify Cellular and Spatial Biomarkers

9:55-10:05  Ruibang Luo

Optimizing long-term prevention of cardiovascular disease with reinforcement learning

10:05-10:15  Soichi Ogishima

Leveraging Large-scale Genome Cohorts: AI-Driven Prediction Model for Precision Prevention

10:15-10:25  Guoqiang Yu

Quantification and analysis of molecular spatiotemporal signals with advanced machine learning techniques

10:25-10:35  Hebing Chen

DNA Damage and Three-dimensional Genome

10:35-10:45  Anders Skanderup

AI-driven molecular diagnostics in oncology

10:35-11:00

Break

 

 

 

11:00-12:00

Session 2  AI foundation models for DNA, RNA and proteins

Moderator: Xiaowo Wang/Zhihua Zhang

11:00-11:10   Tiannan Guo

Grow AI virtual cells with perturbation proteomics  

11:10-11:20   Jian Lu

AI-driven analysis of protein translation efficiency through RNA biology integration

11:20-11:30   Qiangfeng Zhang

Advancing Structural Biology: Harnessing AI Foundation Models for Precision Molecular Structure Determination

11:30-11:40 Stephen Bush

ANNEVO: A Mixture-of-Experts Genomic Language Model for Evidence-Free, Evolution-Aware Gene Annotation  

11:40-11:50  Louxin Zhang

HIG-Syn: A Hypergraph and Interaction-Aware Deep Learning Model for Precision Prediction of Synergistic Drug Combinations  

 

11:50 - 12:00  Yuanhua Huang

Assessing large-scale genomic language models in predicting personal gene expression: promises and limitations

12:00-13:00

Lunch

13:00-14:00

Group Discussion: Artificial intelligence vs. human intelligence:  Opportunities and concerns 

Coordinator: Xiujie Wang

Discussants: Yixue Li, Shihua Zhang, Lu Xie, Zhang Zhang, Zhiwei Cao

14:00-14:20

Group Picture

14:20-16:20

Group Activity

16:20

Shuffle Bus to Prama Sanur Beach Hotel

18:00-20:00

Welcome Dinner at Beach

 

June 1st

8:30

Gathering at Prama Sanur Beach Hotel

8:30-9:00

Shuttle Bus to Tsinghua Southeast Asia Center

9:00-9:30

Keynotes: Towards a cell in silico

Speaker: Ge Gao

Moderator: Kai Ye 

 

 

 

9:30-10:40

Session 3 AI for single-cell, spatial omics and multi-omics 

Moderator:Shihua Zhang(Hairong Lv)/Hongmin Cai/Qi LiuXiaofeng Song

9:30-9:40   Boxiang Liu

Ancestry- and Sex-Biased Alternative Splicing in Immune Cells: Single-Cell Insights from the Asian Immune Diversity Atlas

9:40-9:50   Xun Xu

Multi-omics Single-cell Technologies for Cell-LLM  

9:50-10:00   Loza Martin

AI-Powered Spatial and Single-Cell Omics Analysis: STAIG and HyGAnno for Enhanced Domain Detection and Cell Type Annotation

10:00-10:10 Lin Hou

CausalPerturb: AI-Powered Causal Inference for Decoding Single-Cell CRISPR Perturbation Heterogeneity

10:10-10:20 Zhiwei Cao

Multi-omics-based AI discovery for lung cancer

10:20-10:30 Aziz Khan

Towards FAIR, diverse and reproducible multi-omics for AI-driven biology

10:30-10:40  Jiguang Wang

AI-Powered Multi-Omics Integration for Enhanced Cancer Subtyping

10:40-11:10

Break

 

 

 

11:10-11:50

Session 4

AI for microbiology, metagenomics & industrial Applications

Moderator: Zhang Zhang/Yixue Li

11:10-11:20   Weihua Chen

Best Practices for Developing Microbiome-Based Disease Diagnostic Classifiers through Machine Learning

11:20-11:30   Shuhua Xu

AI for Human Evolution

11:30-11:40  Limsoon WONG

SORCERER: Second-Order Relational Contrastive Learning for Robust Knowledge Graph Reasoning

11:40-11:50  Joshua Ho

AI vs. Cardiologists in Murmur Detection: A Prospective Clinical Benchmark Using Smartphones and Digital Stethoscopes

11:50-12:00  Gang Chen

From Million Personal Genomes to Personal Omics Intelligence

12:00-13:00

Lunch

13:00-14:00

Group Discussion:Are we assessing the performance of AI on computational biology problems properly?Time for some guidelines

CoordinatorLimsoon Wong

Discussants: Joshuo Ho, Jiangning Song, Tsung Fei Khang, Lin Hou

14:00-17:30

Cultural Activity

17:30

Shuffle Bus to Prama Sanur Beach Hotel

June 2nd

8:30

Gathering at Prama Sanur Beach Hotel

8:30-8:50

Shuffle Bus to Tsinghua Southeast Asia Center

 

 

 

9:00-10:00

Session 5 AI-Enabled Precision Medicine & Biomarker Discovery

ModeratorTingting Li/Weiwei Zhai

9:00 - 9:10  Jiangning Song

Accelerating Biomedical Discovery Through Machine Learning: A Unified Framework for Multi-Dimensional Molecular Data Analysis   

9:10-9:20  Guoliang Li

Title: Identification of pan-cancer differentially methylated regions enables non-invasive diagnosis of seven cancer types.

9:20-9:30  Youqiong Ye

 Cellular Senescence Detection via Single-cell Foundation Model Identifies Spatially-resolved Senescent Programs Driving Tumor Immune Evasion

9:30-9:40  Toshiaki Katayama

Technological Developments for Integrating Life Science Knowledge Graphs

10:00-10:20

Break

10:20-11:20

Panel DiscussionInternational Academic Exchanges and Collaborations in AI Computational Biology in the New Era

CoordinatorXuegong Zhang

Limsoon Wong, Joshua Ho, Aziz Khan, KHANG Tsung Fei, Toshiaki Katayama, Xingming Zhao, Kai Ye

11:20-11:30

Closing Remarks - Xiujie Wang

ModeratorXuegong Zhang

11:30-12:30

Lunch

12:30

Shuttle Bus to Prama Sanur Beach Hotel

 

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